International Consortium for Blood Pressure
Jo Knight is on the International Consortium for Blood Pressure 1000 Genome Analysis group. The consortium have undertaken a meta analysis on more than 150,000 samples and identified new genetic risk loci for elevated blood pressure. They have also used gene expression data to provide further evidence of the functional involvement of the genes.
The work is reported in the following two manuscripts:
- Warren HR et al. Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics. 2017 Feb 20;49:403-415. DOI: 10.1038/ng.3768
- Wain LV, et al. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension. 2017 Jul 24. DOI: 10.1161/HYPERTENSIONAHA.117.09438. [Epub ahead of print]